产品货号:
Z29348
中文名称:
ULBP3抗体
英文名称:
Anti-ULBP3 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ULBP3 Antibody |
指标别名 | UL16-binding protein 3;ALCAN-gamma;NKG2D ligand 3;N2DL-3;NKG2DL3;Retinoic acid early transcript 1N;ULBP3;N2DL3;RAET1N |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | ULBP3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
计算分子量 | 28KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | N2DL3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | UL16 binding protein 3 (ULBP3) is a cell surface glycoprotein encoded by ULBP3 gene located on the chromosome 6.It is mapped to 6q25.1.ULBP3 is related to MHC class I molecules,but its gene maps outside the MHC locus.The domain structure of ULBP3 differs significantly from those of conventional MHC class I molecules.It does not contain the α3 domain and the transmembrane segment.ULBP3 is thus composed of only the α1α2 domain which is linked to the cell membrane by the GPI anchor.It functions as a stress-induced ligand for NKG2D receptor.The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor,which is found in primary NK cells.Binding of these ligands to the receptor activates several signal transduction pathways,including the JAK2,STAT5,and ERK pathways.The encoded protein is expressed solubly and on the surface of many tumor cells,making it potentially an important target for therapeutics. |
Uniprot ID | Q9BZM4 |
基因名全称 | UL16-binding protein 3 |
蛋白名全称 | UL16-binding protein 3 |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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